Found Description
Overview
Role: Lead or support the development, optimisation and validation of bioassays and analytical methods for testing monoclonal antibodies (mAbs) and next-generation biologics, including antibody-drug conjugates (ADCs), bispecific antibodies, single-chain variable fragments (scFvs), and antibody-oligonucleotide conjugates (AOCs), to support quality and safety assessment.
Responsibilities
- Technical Excellence & Method Development: Develop and validate bioassays such as ADCC/CDC activity and cytotoxicity assessment for monoclonal antibodies and advanced biologics (including ADCs, bispecifics, scFvs, and AOCs).
- Develop and validate analytical methods using SPR or BLI to assess complex binding interactions, or using HRMS to support structural characterization, drug-to-antibody ratio determination, and conjugation site analysis.
- Lead or support the development of platform methods for physicochemical characterization acr...
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