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Senior Scientist Computational Biologist

Actalent

Rockville, MD, United States Full-time February 21, 2026

Found Description

Job Title: Scientist Computational Biologist
Job Description
In this computational biology role, you will be part of the antibody engineering group with a focus on cancer therapeutics. You will apply deep learning and physics-based models to design and optimize monoclonal and bispecific antibodies. The role combines physics-based and emerging AI/ML approaches to analyze structural and NGS data, guiding structure prediction, engineering for affinity and developability, and display library design. This position involves approximately 90% computational work and 10% bench work, requiring a self-motivated individual who thrives in collaborative, interdisciplinary environments.
Responsibilities

+ Contribute to the development of computational methods to engineer and optimize monoclonal and bispecific antibody therapeutics for cancer treatment.

+ Review literature, apply and benchmark computational methods, especially emerging deep-learning methods, for antibody eng...

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